Last update
10/6/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
13 mcg (500 IU)
63%
Calcium (as Calcium Citrate)
630 mg
48%
Top Medical Research Studies
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More
Most Useful Reviews
9
Sleep issue resolution
Inexpensive yet excellent vitamin. Initially, I experienced slight bloating, but it subsided. After using it, I noticed stronger teeth, and my joints stopped making noise. Surprisingly, it helped with my insomnia; within half an hour of taking the tablet, I fell asleep. An outstanding product, I'll definitely repurchase.
Read More
7.5
Improved sleep quality
1 people found this helpful
Calcium plus D3 Sugar, salt (sodium chloride) and excess protein hinder calcium absorption, increasing calcium excretion in urine. If dietary calcium is insufficient, it is drawn from bones. Sugary drinks, including non-carbonated juices and colas, significantly elevate fracture risks. Soft drinks worsen the situation due to sugar and acid phosphates, leading to greater calcium loss. I find calcium absorbs well with D3. I take it at night, and it has improved my sleep.
Read More
7.5
Sleep enhancement noted
Easy to digest and absorb. After taking it for a year, my knee issue improved. I always take it before bed, which enhances my sleep.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Sleep issue resolution
Inexpensive yet excellent vitamin. Initially, I experienced slight bloating, but it subsided. After using it, I noticed stronger teeth, and my joints stopped making noise. Surprisingly, it helped with my insomnia; within half an hour of taking the tablet, I fell asleep. An outstanding product, I'll definitely repurchase.
Read More
7.5
Improved sleep quality
1 people found this helpful
Calcium plus D3 Sugar, salt (sodium chloride) and excess protein hinder calcium absorption, increasing calcium excretion in urine. If dietary calcium is insufficient, it is drawn from bones. Sugary drinks, including non-carbonated juices and colas, significantly elevate fracture risks. Soft drinks worsen the situation due to sugar and acid phosphates, leading to greater calcium loss. I find calcium absorbs well with D3. I take it at night, and it has improved my sleep.
Read More
7.5
Sleep enhancement noted
Easy to digest and absorb. After taking it for a year, my knee issue improved. I always take it before bed, which enhances my sleep.
Read More
6
Supports sleep health
Good quality and packaging. This supplement, when taken alongside magnesium, may even ameliorate knee pain. It effectively addresses calcium deficiency, making it suitable for older individuals to protect bones and improve sleep.
Read More
Frequently Asked Questions
9
Sleep issue resolution
Inexpensive yet excellent vitamin. Initially, I experienced slight bloating, but it subsided. After using it, I noticed stronger teeth, and my joints stopped making noise. Surprisingly, it helped with my insomnia; within half an hour of taking the tablet, I fell asleep. An outstanding product, I'll definitely repurchase.
7.5
Sleep enhancement noted
Easy to digest and absorb. After taking it for a year, my knee issue improved. I always take it before bed, which enhances my sleep.
7.5
Improved sleep quality
1 people found this helpful
Calcium plus D3 Sugar, salt (sodium chloride) and excess protein hinder calcium absorption, increasing calcium excretion in urine. If dietary calcium is insufficient, it is drawn from bones. Sugary drinks, including non-carbonated juices and colas, significantly elevate fracture risks. Soft drinks worsen the situation due to sugar and acid phosphates, leading to greater calcium loss. I find calcium absorbs well with D3. I take it at night, and it has improved my sleep.
6
Supports sleep health
Good quality and packaging. This supplement, when taken alongside magnesium, may even ameliorate knee pain. It effectively addresses calcium deficiency, making it suitable for older individuals to protect bones and improve sleep.
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
References
- Kilavuz A, Celikhisar H, Dasdemir Ilkhan G. The Association of Serum 25(OH) Vitamin D Level with Severity of Obstructive Sleep Apnea Syndrome in Patients with Syndrome Z (the Interaction of Obstructive Sleep Apnea with Metabolic Syndrome). Metab Syndr Relat Disord. 2021;19:549. 10.1089/met.2021.0066
- Ayyıldız F, Yıldıran H, Afandiyeva N, Gülbahar Ö, Köktürk O. The effects of vitamin D supplemantation on prognosis in patients with mild obstructive sleep apnea syndrome. Turk J Med Sci. 2021;51:2524. 10.3906/sag-2101-83
- Kerley CP, Hutchinson K, Bramham J, McGowan A, Faul J, et al. Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study. J Clin Sleep Med. 2017;13:19. 10.5664/jcsm.6378
